Abstract
Kidney cancer is the third urologic cancer, its metastases are often found in a known cancer context. We report the clinical observations of two kidney cancers revealed by neurological manifestations. Cases : Case 1 : Mr. A.M aged 43 consulted for right hemiparesis with progressive installation, the radiological assessment showed a fronto‑parietal brain tumor. Histopathological and immunohistochemical study of the tumor showed a renal cell carcinoma metastasis. Case 2 : Mr. S.B, aged 43 consulted for spinal pain with flaccid paraplegia lasting for 3 months, the balance sheet showed an osteolytic and compressive spinal injury, then a left voluminous medio‑renal mass . Conclusion: Brain metastases from kidney are rare, the most histological subtype concerned is clear cell carcinoma. Whatever the metastasis treatment is, nephrectomy must always be done.

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